Clinical Trials in Las Vegas

Now enrolling: **STOP-HAE** — a breakthrough HAE prevention trial

We’re excited to offer cutting-edge clinical research in Southern Nevada. Led by Dr. Jason Bellak, our team is bringing innovative HAE treatments to Las Vegas — starting with the STOP-HAE trial. More studies coming soon.

Patient Information

Contact Us to Learn More or Enroll:

Interested in the STOP-HAE trial or future studies? Email info@vegasallergy.com or call 702-360-6100 and ask for a study coordinator. Our team will guide you through eligibility and next steps.

Introduction to Our Clinical Research:

At the Allergy & Asthma Center of Las Vegas, we’re dedicated to pioneering treatments for allergy, asthma, and immunology conditions. Our entry into clinical trials allows us to offer cutting-edge options like the STOP-HAE study, which explores a new investigational drug (ADX-324) for preventing HAE attacks. This siRNA-based therapy targets prekallikrein (PKK) to reduce attack frequency and severity, potentially with injections every 3-6 months—easing the burden of daily or weekly treatments.

Current Trial: STOP-HAE

The STOP-HAE clinical trial is evaluating ADX-324 for adults with HAE Type I or II. By participating, you’ll contribute to HAE advancements while receiving close monitoring from our expert team.

  • What is ADX-324? A small interfering RNA (siRNA) that blocks PKK production, preventing attacks without altering DNA.

Study Phases:

  • Screening (4-8 weeks): Medical history review, eDiary setup for tracking attacks, vital signs, ECG, blood/urine tests.

  • Treatment (25 weeks): Randomized to ADX-324 (high/low dose) or placebo; subcutaneous injections; regular check-ins (clinic or home visits possible).
  • Optional Extension (up to 3 years): Open-label ADX-324 for all eligible participants.

Eligibility Criteria:

  • Age 18+
  • Diagnosed with HAE Type I or II
  • Willing to pause preventive medications
  • Access to effective acute therapy
  • No interfering medical conditions (e.g., hypertension)
  • Ability to use an eDiary app
  • (Full assessment by our study doctor; this is not exhaustive.)

What to Expect: No cost for study procedures; possible reimbursement for travel/rescue meds. Risks discussed upfront; continue rescue medications as needed.

Why Participate? Gain insights into managing your HAE, access potential new treatments, and help shape future care.

Book Your Appointment for Allergy or Asthma Treatment in Las Vegas

The Allergy and Asthma Center of Las Vegas is currently accepting new patients. We accept most insurance plans and gladly file claims on your behalf. To best accommodate our patients’ busy schedules, we offer extended evening hours on Wednesday, and early morning appointments on Friday. Request an appointment online or call 702-360-6100.